INSTIs for the management of HIV-associated TB (INSIGHT study): a phase 2b study to evaluate the efficacy, safety and pharmacokinetics of a combination of bictegravir, emtricitabine and tenofovir alafenamide fumarate for the treatment of HIV-1 infection in patients with drug-susceptible tuberculosis on a rifampicin-based treatment regimen: a phase 2b open-label randomised controlled trial

INTRODUCTION: Cotreatment of HIV and tuberculosis (TB) reduces morbidity and mortality in coinfected patients. Availability of antiretroviral treatment (ART) drug options, including within drug classes, is important, particularly in high HIV/TB burden low and middle-income countries. METHODS AND ANA...

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Detalles Bibliográficos
Autores principales: Naidoo, Anushka, Dooley, Kelly E, Naidoo, Kogieleum, Padayatchi, Nesri, Yende-Zuma, Nonhlanhla, Perumal, Rubeshan, Dorse, Gillian, Boodhram, Resha, Osuala, Emmanuella Chinonso
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BMJ Publishing Group 2022
Materias:
Pharmacology and Therapeutics
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9660663/
https://www.ncbi.nlm.nih.gov/pubmed/36356989
http://dx.doi.org/10.1136/bmjopen-2022-067765

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9660663/
https://www.ncbi.nlm.nih.gov/pubmed/36356989
http://dx.doi.org/10.1136/bmjopen-2022-067765

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