Cargando…

Multiregion single cell analysis reveals a novel subtype of cancer-associated fibroblasts located in the hypoxic tumor microenvironment in colorectal cancer

BACKGROUND: : The tumor microenvironment (TME) plays a critical role in shaping tumor progression and determining the outcome of the therapeutic response. In this study, we aimed to generate a comprehensive cellular landscape of the colorectal cancer (CRC) TME. METHODS: : We generated a comprehensiv...

Descripción completa

Detalles Bibliográficos
Autores principales: Zheng, Nanxin, Wen, Rongbo, Zhou, Leqi, Meng, Qingying, Zheng, Kuo, Li, Zhixuan, Cao, Fuao, Zhang, Wei
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Neoplasia Press 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9660844/
https://www.ncbi.nlm.nih.gov/pubmed/36371957
http://dx.doi.org/10.1016/j.tranon.2022.101570