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Multiregion single cell analysis reveals a novel subtype of cancer-associated fibroblasts located in the hypoxic tumor microenvironment in colorectal cancer
BACKGROUND: : The tumor microenvironment (TME) plays a critical role in shaping tumor progression and determining the outcome of the therapeutic response. In this study, we aimed to generate a comprehensive cellular landscape of the colorectal cancer (CRC) TME. METHODS: : We generated a comprehensiv...
Autores principales: | Zheng, Nanxin, Wen, Rongbo, Zhou, Leqi, Meng, Qingying, Zheng, Kuo, Li, Zhixuan, Cao, Fuao, Zhang, Wei |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Neoplasia Press
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9660844/ https://www.ncbi.nlm.nih.gov/pubmed/36371957 http://dx.doi.org/10.1016/j.tranon.2022.101570 |
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