Cargando…

Co-encapsulation of paclitaxel and 5-fluorouracil in folic acid-modified, lipid-encapsulated hollow mesoporous silica nanoparticles for synergistic breast cancer treatment

A dual-loaded multi-targeted drug delivery nanosystem was constructed to simultaneously load paclitaxel (PTX) and 5-fluorouracil (5-FU) for targeted delivery and sustained release at tumor sites. Hollow mesoporous silica nanoparticles (HMSNs) were prepared by the inverse microemulsion method, then m...

Descripción completa

Detalles Bibliográficos
Autores principales: Yin, Huanli, Yan, Qi, Liu, Yuan, Yang, Lan, Liu, Yang, Luo, Yujie, Chen, Tianyu, Li, Ningxi, Wu, Min
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Royal Society of Chemistry 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9661185/
https://www.ncbi.nlm.nih.gov/pubmed/36425719
http://dx.doi.org/10.1039/d2ra03718a