Cargando…

Interactive contribution of hyperinsulinemia, hyperglycemia, and mammalian target of rapamycin signaling to valvular interstitial cell differentiation and matrix remodeling

Diabetes and its major key determinants insulin resistance and hyperglycemia are known risk factors for calcific aortic valve disease (CAVD). The processes leading to molecular and structural alterations of the aortic valve are yet not fully understood. In previous studies, we could show that valvul...

Descripción completa

Detalles Bibliográficos
Autores principales:	Selig, Jessica I., Krug, H. Viviana, Küppers, Caroline, Ouwens, D. Margriet, Kraft, Felix A., Adler, Elena, Bauer, Sebastian J., Lichtenberg, Artur, Akhyari, Payam, Barth, Mareike
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Frontiers Media S.A. 2022
Materias:	Cardiovascular Medicine
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9661395/ https://www.ncbi.nlm.nih.gov/pubmed/36386326 http://dx.doi.org/10.3389/fcvm.2022.942430

Ejemplares similares

Crosstalk of Diabetic Conditions with Static Versus Dynamic Flow Environment—Impact on Aortic Valve Remodeling
por: Selig, Jessica I., et al.
Publicado: (2021)

Reproducible In Vitro Tissue Culture Model to Study Basic Mechanisms of Calcific Aortic Valve Disease: Comparative Analysis to Valvular Interstitials Cells
por: Weber, Andreas, et al.
Publicado: (2021)

PPAR-Gamma Activation May Inhibit the In Vivo Degeneration of Bioprosthetic Aortic and Aortic Valve Grafts under Diabetic Conditions
por: Katahira, Shintaro, et al.
Publicado: (2021)

Degeneration of Aortic Valves in a Bioreactor System with Pulsatile Flow
por: Niazy, Naima, et al.
Publicado: (2021)

An Innovative Method for Exosome Quantification and Size Measurement
por: Mehdiani, Arash, et al.
Publicado: (2015)

Three-Dimensional Bioprinting of Ovine Aortic Valve Endothelial and Interstitial Cells for the Development of Multicellular Tissue Engineered Tissue Constructs
por: Immohr, Moritz Benjamin, et al.
Publicado: (2023)

Hyperinsulinemia and hyperglycemia: risk factors for recurrence of benign paroxysmal positional vertigo()()
por: Webster, Guilherme, et al.
Publicado: (2015)

Ventricular stabilization with a customized decellularized cardiac ECM-based scaffold after myocardial infarction alters gene expression in a rodent LAD-ligation model
por: Aubin, Hug, et al.
Publicado: (2022)

Degenerative changes of the aortic valve during left ventricular assist device support
por: Barth, Mareike, et al.
Publicado: (2021)

Focal induction of ROS-release to trigger local vascular degeneration
por: Minol, Jan-Philipp, et al.
Publicado: (2017)

A Role for Peroxisome Proliferator-Activated Receptor Gamma Agonists in Counteracting the Degeneration of Cardiovascular Grafts
por: Assmann, Anna Kathrin, et al.
Publicado: (2022)

Resveratrol potentiates rapamycin to prevent hyperinsulinemia and obesity in male mice on high fat diet
por: Leontieva, O V, et al.
Publicado: (2013)

Short-Term Hyperinsulinemia and Hyperglycemia Increase Myocardial Lipid Content in Normal Subjects
por: Winhofer, Yvonne, et al.
Publicado: (2012)

Hyperinsulinemia Down-Regulates TLR4 Expression in the Mammalian Heart
por: de Laat, Melody A., et al.
Publicado: (2014)

Mechanism for the synergistic effect of rapamycin and resveratrol on hyperinsulinemia may involve the activation of protein kinase B
por: Chen, J, et al.
Publicado: (2013)

A Novel Strategy in Production of Oligosaccharides in Digestive Tract: Prevention of Postprandial Hyperglycemia and Hyperinsulinemia
por: Sasaki, Makoto, et al.
Publicado: (2007)

Restoration of Lepr in β cells of Lepr null mice does not prevent hyperinsulinemia and hyperglycemia
por: D'souza, Anna M., et al.
Publicado: (2017)

Additional right-sided upper “Half-Mini-Thoracotomy” for aortocoronary bypass grafting during minimally invasive multivessel revascularization
por: Aubin, Hug, et al.
Publicado: (2015)

Late reoperation after proximal repair of supravalvular stenosis for diffuse form of Williams–Beuren syndrome
por: Katahira, Shintaro, et al.
Publicado: (2020)

Whole-Blood Tissue Factor Procoagulant Activity Is Elevated in Type 1 Diabetes: Effects of hyperglycemia and hyperinsulinemia
por: Singh, Anamika, et al.
Publicado: (2012)

Corrigendum to: Multimodal temporary mechanically circulatory assistance for primary graft dysfunction after heart transplantation: a case report
por: Immohr, Moritz B, et al.
Publicado: (2022)

Atrial Thrombosis Caused by a Dislocated Left Atrial Appendage Closure Device After Mitral Valve Replacement
por: Immohr, Moritz B., et al.
Publicado: (2020)

Multimodal temporary mechanically circulatory assistance for primary graft dysfunction after heart transplantation: a case report
por: Immohr, Moritz B, et al.
Publicado: (2021)

Skeletal muscle autophagy remains responsive to hyperinsulinemia and hyperglycemia at higher plasma insulin concentrations in insulin‐resistant mice
por: Ehrlicher, Sarah E., et al.
Publicado: (2018)

Resolvin E1 derived from eicosapentaenoic acid prevents hyperinsulinemia and hyperglycemia in a host genetic manner
por: Pal, Anandita, et al.
Publicado: (2020)

The Cholesterol Metabolite Cholest-5-en-3-One Alleviates Hyperglycemia and Hyperinsulinemia in Obese (db/db) Mice
por: Nagao, Koji, et al.
Publicado: (2021)

Rapamycin-induced hyperglycemia is associated with exacerbated age-related osteoarthritis
por: Minton, Dennis M., et al.
Publicado: (2021)

Altered mRNA Expression of Interleukin-1 Receptors in Myocardial Tissue of Patients with Left Ventricular Assist Device Support
por: Niazy, Naima, et al.
Publicado: (2021)

Hyperinsulinemia Associated Depression
por: Sarwar, Haider, et al.
Publicado: (2022)

The mammalian target of rapamycin contributes to synovial fibroblast pathogenicity in rheumatoid arthritis
por: Barker, Brianne E., et al.
Publicado: (2023)

Iatrogenic Hyperinsulinemia, Not Hyperglycemia, Drives Insulin Resistance in Type 1 Diabetes as Revealed by Comparison With GCK-MODY (MODY2)
por: Gregory, Justin M., et al.
Publicado: (2019)

Lifestyle Therapy Targeting Hyperinsulinemia Normalizes Hyperglycemia and Surrogate Markers of Insulin Resistance in a Large, Free-Living Population
por: Cummings, Peter J., et al.
Publicado: (2022)

Correction to: Rapamycin-induced hyperglycemia is associated with exacerbated age-related osteoarthritis
por: Minton, Dennis M., et al.
Publicado: (2022)

Rheb and mammalian target of rapamycin in mitochondrial homoeostasis
por: Groenewoud, Marlous J., et al.
Publicado: (2013)

Parathyroid Hormone Induces Human Valvular Endothelial Cells Dysfunction That Impacts the Osteogenic Phenotype of Valvular Interstitial Cells
por: Vadana, Mihaela, et al.
Publicado: (2022)

Defective Glycogenesis Contributes Toward the Inability to Suppress Hepatic Glucose Production in Response to Hyperglycemia and Hyperinsulinemia in Zucker Diabetic Fatty Rats
por: Torres, Tracy P., et al.
Publicado: (2011)

Inhibiting PI3K reduces mammary tumor growth and induces hyperglycemia in a mouse model of insulin resistance and hyperinsulinemia
por: Gallagher, Emily Jane, et al.
Publicado: (2011)

High-Fat Programming of Hyperglycemia, Hyperinsulinemia, Insulin Resistance, Hyperleptinemia, and Altered Islet Architecture in 3-Month-Old Wistar Rats
por: Cerf, Marlon E., et al.
Publicado: (2012)

Characterization of Porcine Aortic Valvular Interstitial Cell ‘Calcified’ Nodules
por: Cloyd, Kristy L., et al.
Publicado: (2012)

Robust Generation of Quiescent Porcine Valvular Interstitial Cell Cultures
por: Porras, Ana M., et al.
Publicado: (2017)

Cannot write session to /tmp/vufind_sessions/sess_68ic8205u2ea9pkv6cclk0batm