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Flash drug release from nanoparticles accumulated in the targeted blood vessels facilitates the tumour treatment

Tumour microenvironment hinders nanoparticle transport deep into the tissue precluding thorough treatment of solid tumours and metastatic nodes. We introduce an anticancer drug delivery concept termed FlaRE (Flash Release in Endothelium), which represents alternative to the existing approaches based...

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Detalles Bibliográficos
Autores principales: Zelepukin, Ivan V., Griaznova, Olga Yu., Shevchenko, Konstantin G., Ivanov, Andrey V., Baidyuk, Ekaterina V., Serejnikova, Natalia B., Volovetskiy, Artur B., Deyev, Sergey M., Zvyagin, Andrei V.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9661469/
https://www.ncbi.nlm.nih.gov/pubmed/36376302
http://dx.doi.org/10.1038/s41467-022-34718-3