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Flash drug release from nanoparticles accumulated in the targeted blood vessels facilitates the tumour treatment
Tumour microenvironment hinders nanoparticle transport deep into the tissue precluding thorough treatment of solid tumours and metastatic nodes. We introduce an anticancer drug delivery concept termed FlaRE (Flash Release in Endothelium), which represents alternative to the existing approaches based...
Autores principales: | Zelepukin, Ivan V., Griaznova, Olga Yu., Shevchenko, Konstantin G., Ivanov, Andrey V., Baidyuk, Ekaterina V., Serejnikova, Natalia B., Volovetskiy, Artur B., Deyev, Sergey M., Zvyagin, Andrei V. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9661469/ https://www.ncbi.nlm.nih.gov/pubmed/36376302 http://dx.doi.org/10.1038/s41467-022-34718-3 |
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