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Aptamer–Protein Structures Guide In Silico and Experimental Discovery of Aptamer–Short Peptide Recognition Complexes or Aptamer–Amino Acid Cluster Complexes

[Image: see text] A method to computationally and experimentally identify aptamers against short peptides or amino acid clusters is introduced. The method involves the selection of a well-defined protein aptamer complex and the extraction of the peptide sequence participating in the binding of the p...

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Detalles Bibliográficos
Autores principales: Fadeev, Michael, O’Hagan, Michael P., Biniuri, Yonatan, Willner, Itamar
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Chemical Society 2022
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9661473/
https://www.ncbi.nlm.nih.gov/pubmed/36315022
http://dx.doi.org/10.1021/acs.jpcb.2c05624