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ATF5 is a regulator of exercise-induced mitochondrial quality control in skeletal muscle

OBJECTIVES: The Mitochondrial Unfolded Protein Response (UPR(mt)) is a compartment-specific mitochondrial quality control (MQC) mechanism that uses the transcription factor ATF5 to induce the expression of protective enzymes to restore mitochondrial function. Acute exercise is a stressor that has th...

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Detalles Bibliográficos
Autores principales: Slavin, Mikhaela B., Kumari, Rita, Hood, David A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9661517/
https://www.ncbi.nlm.nih.gov/pubmed/36332794
http://dx.doi.org/10.1016/j.molmet.2022.101623