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ATF5 is a regulator of exercise-induced mitochondrial quality control in skeletal muscle
OBJECTIVES: The Mitochondrial Unfolded Protein Response (UPR(mt)) is a compartment-specific mitochondrial quality control (MQC) mechanism that uses the transcription factor ATF5 to induce the expression of protective enzymes to restore mitochondrial function. Acute exercise is a stressor that has th...
Autores principales: | , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Elsevier
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9661517/ https://www.ncbi.nlm.nih.gov/pubmed/36332794 http://dx.doi.org/10.1016/j.molmet.2022.101623 |