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The G-Protein-Coupled Estrogen Receptor Agonist Prevents Cardiac Lipid Accumulation by Stimulating Cardiac Peroxisome Proliferator-Activated Receptor α: A Preclinical Study in Ovariectomized-Diabetic Rat Model

BACKGROUND: Type 2 diabetes mellitus (T2DM) is associated with cardiometabolic changes, and menopause exacerbates these conditions, leading to a greater risk of cardiovascular diseases (CVDs). The G protein-coupled estrogen receptor (GPER), which mediates the rapid effects of estrogen, has beneficia...

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Detalles Bibliográficos
Autores principales: Jafarynezhad, Faezeh, Shahbazian, Mohammad, Farhadi, Zeinab, Yadeghari, Maryam, Rezvani, Mohammad Ebrahim, Safari, Fatemeh, Azizian, Hossein
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Brieflands 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9661540/
https://www.ncbi.nlm.nih.gov/pubmed/36407026
http://dx.doi.org/10.5812/ijem-123560