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The G-Protein-Coupled Estrogen Receptor Agonist Prevents Cardiac Lipid Accumulation by Stimulating Cardiac Peroxisome Proliferator-Activated Receptor α: A Preclinical Study in Ovariectomized-Diabetic Rat Model
BACKGROUND: Type 2 diabetes mellitus (T2DM) is associated with cardiometabolic changes, and menopause exacerbates these conditions, leading to a greater risk of cardiovascular diseases (CVDs). The G protein-coupled estrogen receptor (GPER), which mediates the rapid effects of estrogen, has beneficia...
Autores principales: | Jafarynezhad, Faezeh, Shahbazian, Mohammad, Farhadi, Zeinab, Yadeghari, Maryam, Rezvani, Mohammad Ebrahim, Safari, Fatemeh, Azizian, Hossein |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Brieflands
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9661540/ https://www.ncbi.nlm.nih.gov/pubmed/36407026 http://dx.doi.org/10.5812/ijem-123560 |
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