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Development of an insect cell-based adeno-associated virus packaging cell line employing advanced Rep gene expression control system
The insect cell-based baculovirus expression vector (BEV) system is a leading platform for scalable production of adeno-associated viruses (AAVs). The previously described One-Bac system consists of an insect packaging cell line harboring the AAV Rep and Cap genes and a BEV carrying the transgene an...
Autores principales: | , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
American Society of Gene & Cell Therapy
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9661643/ https://www.ncbi.nlm.nih.gov/pubmed/36381303 http://dx.doi.org/10.1016/j.omtm.2022.10.015 |