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Development of an insect cell-based adeno-associated virus packaging cell line employing advanced Rep gene expression control system

The insect cell-based baculovirus expression vector (BEV) system is a leading platform for scalable production of adeno-associated viruses (AAVs). The previously described One-Bac system consists of an insect packaging cell line harboring the AAV Rep and Cap genes and a BEV carrying the transgene an...

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Detalles Bibliográficos
Autores principales:	Moreno, Fiona, Lip, Florence, Rojas, Hugo, Anggakusuma
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	American Society of Gene & Cell Therapy 2022
Materias:	Original Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9661643/ https://www.ncbi.nlm.nih.gov/pubmed/36381303 http://dx.doi.org/10.1016/j.omtm.2022.10.015

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