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Investigating the association of toll-like receptor 9 rs5743836, rs352140, and rs187084 gene polymorphisms and their mRNA levels with different hepatic fibrosis stages of non-alcoholic fatty liver patients compared to healthy controls

Recent studies have shown that the level of hepatocyte-derived mitochondrial DNA is elevated in plasma samples obtained from mice and NASH patients, and it has the ability to toll-like receptor 9 (TLR9) activation resulting in steatosis, hepatocyte injury, and fibrosis. In this study, we explored th...

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Detalles Bibliográficos
Autores principales: Rezaie, Azadeh, Nasiri, Meysam, Hatami, Behzad, Baghaie, Kaveh, Asadzadeh-Aghdaei, Hamid, Zali, Mohammad Reza
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Shiraz University 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9661672/
https://www.ncbi.nlm.nih.gov/pubmed/36718239
http://dx.doi.org/10.22099/mbrc.2022.43852.1753