Inhibition of β-Amyloid Aggregation in Alzheimer’s Disease: The Key Role of (Pro)electrophilic Warheads

[Image: see text] Catechols have been largely investigated as antiaggregating agents toward β-amyloid peptide. Herein, as a follow up of a previous series of hydroxycinnamic derivatives, we synthesized a small set of dihydroxy isomers for exploring the role of the reciprocal position of the two hydr...

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Detalles Bibliográficos
Autores principales: Basagni, Filippo, Naldi, Marina, Ginex, Tiziana, Luque, F. Javier, Fagiani, Francesca, Lanni, Cristina, Iurlo, Matteo, Marcaccio, Massimo, Minarini, Anna, Bartolini, Manuela, Rosini, Michela
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Chemical Society 2022
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9661696/
https://www.ncbi.nlm.nih.gov/pubmed/36385935
http://dx.doi.org/10.1021/acsmedchemlett.2c00410

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9661696/
https://www.ncbi.nlm.nih.gov/pubmed/36385935
http://dx.doi.org/10.1021/acsmedchemlett.2c00410

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