Features and factors that dictate if terminating ribosomes cause or counteract nonsense-mediated mRNA decay

Nonsense-mediated mRNA decay (NMD) is a quality control pathway in eukaryotes that continuously monitors mRNA transcripts to ensure truncated polypeptides are not produced. The expression of many normal mRNAs that encode full-length polypeptides is also regulated by this pathway. Such transcript sur...

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Detalles Bibliográficos
Autores principales: Embree, Caleb M., Abu-Alhasan, Rabab, Singh, Guramrit
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Biochemistry and Molecular Biology 2022
Materias:
JBC Reviews
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9661723/
https://www.ncbi.nlm.nih.gov/pubmed/36244451
http://dx.doi.org/10.1016/j.jbc.2022.102592

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9661723/
https://www.ncbi.nlm.nih.gov/pubmed/36244451
http://dx.doi.org/10.1016/j.jbc.2022.102592

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