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Dynamic monitoring of cerebrospinal fluid circulating tumor DNA to identify unique genetic profiles of brain metastatic tumors and better predict intracranial tumor responses in non-small cell lung cancer patients with brain metastases: a prospective cohort study (GASTO 1028)

BACKGROUND: Due to the blood-brain barrier, plasma is not an ideal source to evaluate the genetic characteristics of central nervous system tumors. Thus, cerebrospinal fluid (CSF) is becoming an alternative biopsy type to evaluate the genetic landscape of intracranial tumors. We aimed to explore the...

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Detalles Bibliográficos
Autores principales: Li, Meichen, Chen, Jing, Zhang, Baishen, Yu, Juan, Wang, Na, Li, Delan, Shao, Yang, Zhu, Dongqin, Liang, Chuqiao, Ma, Yutong, Ou, Qiuxiang, Hou, Xue, Chen, Likun
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9661744/
https://www.ncbi.nlm.nih.gov/pubmed/36372873
http://dx.doi.org/10.1186/s12916-022-02595-8