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Age dependent contribution of entry via the CSF to the overall brain entry of small and large hydrophilic markers

BACKGROUND: Apparent permeability of the blood brain barrier to hydrophilic markers has been shown to be higher in the developing brain. Apart from synthesis in situ, any substance detected in the brain parenchyma can originate from two sources: directly through blood vessels of brain vasculature an...

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Detalles Bibliográficos
Autores principales: Qiu, Fiona, Huang, Yifan, Saunders, Norman R., Habgood, Mark D., Dziegielewska, Katarzyna M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9661750/
https://www.ncbi.nlm.nih.gov/pubmed/36376903
http://dx.doi.org/10.1186/s12987-022-00387-z