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Prognostic value of tumor-infiltrating immune cells and immune checkpoints in elderly head-and-neck squamous cell carcinoma patients undergoing definitive (chemo)radiotherapy

BACKGROUND AND PURPOSE: Tumor-infiltrating lymphocytes (TILs) are associated with locoregional control (LRC) in head-and-neck squamous cell carcinoma (HNSCC) patients undergoing (chemo)radiotherapy. As immunosenescence results in reduced immune activity, the role of TILs in elderly HNSCC patients ma...

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Detalles Bibliográficos
Autores principales: Rühle, Alexander, Todorovic, Jovan, Spohn, Simon S. K., Gkika, Eleni, Becker, Christoph, Knopf, Andreas, Zamboglou, Constantinos, Sprave, Tanja, Werner, Martin, Grosu, Anca-Ligia, Kayser, Gian, Nicolay, Nils H.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9661751/
https://www.ncbi.nlm.nih.gov/pubmed/36376922
http://dx.doi.org/10.1186/s13014-022-02153-9