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The ERα-NRF2 signalling axis promotes bicalutamide resistance in prostate cancer

BACKGROUND: Bicalutamide is a nonsteroidal antiandrogen widely used as a first-line clinical treatment for advanced prostate cancer (PCa). Although patients initially show effective responses to bicalutamide treatment, resistance to bicalutamide frequently occurs and leads to the development of cast...

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Detalles Bibliográficos
Autores principales: Tian, Lei, Peng, Yanfei, Yang, Kuo, Cao, Jiasong, Du, Xiaoling, Liang, Zhixian, Shi, Jiandang, Zhang, Ju
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9661764/
https://www.ncbi.nlm.nih.gov/pubmed/36376959
http://dx.doi.org/10.1186/s12964-022-00979-0