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The ERα-NRF2 signalling axis promotes bicalutamide resistance in prostate cancer
BACKGROUND: Bicalutamide is a nonsteroidal antiandrogen widely used as a first-line clinical treatment for advanced prostate cancer (PCa). Although patients initially show effective responses to bicalutamide treatment, resistance to bicalutamide frequently occurs and leads to the development of cast...
Autores principales: | , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9661764/ https://www.ncbi.nlm.nih.gov/pubmed/36376959 http://dx.doi.org/10.1186/s12964-022-00979-0 |