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AQP5 complements LGR5 to determine the fates of gastric cancer stem cells through regulating ULK1 ubiquitination

BACKGROUND: Cancer stem cells (CSCs) are regarded as the "seed cells" for tumorigenesis, metastasis, recurrence and drug resistance. However, specific surface markers of CSCs of different origins have not been documented. METHODS: Single-cell sequencing was used to analyze the highly expre...

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Detalles Bibliográficos
Autores principales: Zhao, Rou, He, Baoyu, Bie, Qingli, Cao, Jinghe, Lu, Haoran, Zhang, Zhixin, Liang, Jing, Wei, Li, Xiong, Huabao, Zhang, Bin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9661769/
https://www.ncbi.nlm.nih.gov/pubmed/36372898
http://dx.doi.org/10.1186/s13046-022-02532-w