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MiRNA/mRNA network topology in hepatitis virus B-related liver cirrhosis reveals miR-20a-5p/340-5p as hubs initiating fibrosis
BACKGROUND: The pathophysiology of hepatitis B-related liver cirrhosis (HBV-LC) remains unclear. This study aimed to explore the disease mechanisms using topological analysis of the miRNA/mRNA network. METHODS: Paired miRNA/mRNA sequencing was performed with thirty-three peripheral blood mononuclear...
Autores principales: | , , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9661777/ https://www.ncbi.nlm.nih.gov/pubmed/36376845 http://dx.doi.org/10.1186/s12920-022-01390-x |