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Failing the four-gamete test enables exact phasing: the Corners’ Algorithm

BACKGROUND: Failing the four-gamete test for two polymorphic DNA markers is an indication that two or three rather than four haplotypes segregate in the population. The objective of this paper is to show that when just three haplotypes are segregating, all three haplotypes can be fully and unambiguo...

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Detalles Bibliográficos
Autores principales: Gomez-Raya, Luis, Rauw, Wendy M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9661815/
https://www.ncbi.nlm.nih.gov/pubmed/36376786
http://dx.doi.org/10.1186/s12711-022-00763-1