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LCK‐Mediated RIPK3 Activation Controls Double‐Positive Thymocyte Proliferation and Restrains Thymic Lymphoma by Regulating the PP2A‐ERK Axis

Receptor‐interacting protein kinase 3 (RIPK3) is the primary regulator of necroptotic cell death. RIPK3 expression is often silenced in various cancer cells, which suggests that it may have tumor suppressor properties. However, the exact mechanism by which RIPK3 negatively regulates cancer developme...

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Detalles Bibliográficos
Autores principales: Hwang, Sung‐Min, Ha, Yu‐Jin, Koo, Gi‐Bang, Noh, Hyun‐Jin, Lee, A‐Yeon, Kim, Byeong‐Ju, Hong, Sun Mi, Morgan, Michael J., Eyun, Seong‐il, Lee, Dakeun, Roe, Jae‐Seok, Lee, Youngsoo, Kim, You‐Sun
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9661840/
https://www.ncbi.nlm.nih.gov/pubmed/36161785
http://dx.doi.org/10.1002/advs.202204522