Geometric Constraints Regulate Energy Metabolism and Cellular Contractility in Vascular Smooth Muscle Cells by Coordinating Mitochondrial DNA Methylation

Vascular smooth muscle cells (SMCs) can adapt to changes in cellular geometric cues; however, the underlying mechanisms remain elusive. Using 2D micropatterned substrates to engineer cell geometry, it is found that in comparison with an elongated geometry, a square‐shaped geometry causes the nuclear...

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Detalles Bibliográficos
Autores principales: Liu, Han, Liu, Yuefeng, Wang, He, Zhao, Qiang, Zhang, Tao, Xie, Si‐an, Liu, Yueqi, Tang, Yuanjun, Peng, Qin, Pang, Wei, Yao, Weijuan, Zhou, Jing
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2022
Materias:
Research Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9661866/
https://www.ncbi.nlm.nih.gov/pubmed/36106364
http://dx.doi.org/10.1002/advs.202203995

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9661866/
https://www.ncbi.nlm.nih.gov/pubmed/36106364
http://dx.doi.org/10.1002/advs.202203995

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