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Geometric Constraints Regulate Energy Metabolism and Cellular Contractility in Vascular Smooth Muscle Cells by Coordinating Mitochondrial DNA Methylation
Vascular smooth muscle cells (SMCs) can adapt to changes in cellular geometric cues; however, the underlying mechanisms remain elusive. Using 2D micropatterned substrates to engineer cell geometry, it is found that in comparison with an elongated geometry, a square‐shaped geometry causes the nuclear...
Autores principales: | Liu, Han, Liu, Yuefeng, Wang, He, Zhao, Qiang, Zhang, Tao, Xie, Si‐an, Liu, Yueqi, Tang, Yuanjun, Peng, Qin, Pang, Wei, Yao, Weijuan, Zhou, Jing |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
John Wiley and Sons Inc.
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9661866/ https://www.ncbi.nlm.nih.gov/pubmed/36106364 http://dx.doi.org/10.1002/advs.202203995 |
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