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Pexidartinib (PLX3397) through restoring hippocampal synaptic plasticity ameliorates social isolation-induced mood disorders

Social behavior is essential for the well-being and survival of individuals. However, social isolation is a serious public health issue, especially during the COVID-19 pandemic, affecting a significant number of people worldwide, and can lead to serious psychological crises. Microglia, innate immune...

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Detalles Bibliográficos
Autores principales: Wang, Laifa, Wang, Xueqin, Deng, Ling, Zhang, Hui, He, Binsheng, Cao, Wenyu, Cui, Yanhui
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier B.V. 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9661988/
https://www.ncbi.nlm.nih.gov/pubmed/36395673
http://dx.doi.org/10.1016/j.intimp.2022.109436