Molecularly engineering a dual-drug nanoassembly for self-sensitized photodynamic therapy via thioredoxin impairment and glutathione depletion

Photodynamic therapy (PDT) has been extensively investigated as a spatiotemporally noninvasive and controllable modality for cancer treatment. However, the intracellular antioxidant systems mainly consisting of thioredoxin (Trx) and glutathione (GSH) significantly counteract and prevent reactive oxy...

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Detalles Bibliográficos
Autores principales: Zhang, Hongyuan, Kong, Zhiqiang, Wang, Ziyue, Chen, Yao, Zhang, Shenwu, Luo, Cong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Taylor & Francis 2022
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9662020/
https://www.ncbi.nlm.nih.gov/pubmed/36350255
http://dx.doi.org/10.1080/10717544.2022.2141920

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9662020/
https://www.ncbi.nlm.nih.gov/pubmed/36350255
http://dx.doi.org/10.1080/10717544.2022.2141920

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