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Shared IGHV1-69-encoded neutralizing antibodies contribute to the emergence of L452R substitution in SARS-CoV-2 variants

SARS-CoV-2 variants continue to emerge facing established herd immunity. L452R, previously featured in the Delta variant, quickly emerged in Omicron subvariants, including BA.4/BA.5, implying a continued selection pressure on this residue. The underlying links between spike mutations and their selec...

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Detalles Bibliográficos
Autores principales: Yan, Qihong, Hou, Ruitian, Huang, Xiaohan, Zhang, Yanjun, He, Ping, Zhang, Yudi, Liu, Banghui, Wang, Qian, Rao, Haiyue, Chen, Xianying, Zhao, Xinwei, Niu, Xuefeng, Zhao, Jincun, Xiong, Xiaoli, Chen, Ling
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Taylor & Francis 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9662066/
https://www.ncbi.nlm.nih.gov/pubmed/36288106
http://dx.doi.org/10.1080/22221751.2022.2140611