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Chemokine switch regulated by TGF-β1 in cancer-associated fibroblast subsets determines the efficacy of chemo-immunotherapy

Combining immunogenic cell death-inducing chemotherapies and PD-1 blockade can generate remarkable tumor responses. It is now well established that TGF-β1 signaling is a major component of treatment resistance and contributes to the cancer-related immunosuppressive microenvironment. However, whether...

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Detalles Bibliográficos
Autores principales: Vienot, Angélique, Pallandre, Jean-René, Renaude, Elodie, Viot, Julien, Bouard, Adeline, Spehner, Laurie, Kroemer, Marie, Abdeljaoued, Syrine, van der Woning, Bas, de Haard, Hans, Loyon, Romain, Hervouet, Eric, Peixoto, Paul, Borg, Christophe
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Taylor & Francis 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9662195/
https://www.ncbi.nlm.nih.gov/pubmed/36387055
http://dx.doi.org/10.1080/2162402X.2022.2144669