A multi‐model approach to predict efficacious clinical dose for an anti‐TGF‐β antibody (GC2008) in the treatment of osteogenesis imperfecta

Osteogenesis imperfecta (OI) is a heterogeneous group of inherited bone dysplasias characterized by reduced skeletal mass and bone fragility. Although the primary manifestation of the disease involves the skeleton, OI is a generalized connective tissue disorder that requires a multidisciplinary trea...

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Detalles Bibliográficos
Autores principales: Mavroudis, Panteleimon D., Pillai, Nikhil, Wang, Qingping, Pouzin, Clemence, Greene, Benjamin, Fretland, Jennifer
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2022
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9662198/
https://www.ncbi.nlm.nih.gov/pubmed/36004727
http://dx.doi.org/10.1002/psp4.12857

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9662198/
https://www.ncbi.nlm.nih.gov/pubmed/36004727
http://dx.doi.org/10.1002/psp4.12857

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