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Population pharmacokinetics modeling and exposure‐response analyses of cemiplimab in patients with recurrent or metastatic cervical cancer

A population pharmacokinetic (PopPK) model was previously developed for cemiplimab in patients with solid tumors, including advanced cutaneous squamous cell carcinoma (CSCC). Here, we update the existing PopPK model and characterize exposure‐response relationships using efficacy and safety data obta...

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Detalles Bibliográficos
Autores principales: Nguyen, Jenny‐Hoa, Epling, Daniel, Dolphin, Nancy, Paccaly, Anne, Conrado, Daniela, Davis, John D., Al‐Huniti, Nidal
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9662200/
https://www.ncbi.nlm.nih.gov/pubmed/36251220
http://dx.doi.org/10.1002/psp4.12855