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Atractylodes lancea for cholangiocarcinoma: Modulatory effects on CYP1A2 and CYP3A1 and pharmacokinetics in rats and biodistribution in mice

Atractylodes lancea (Thunb.) DC. (A. lancea: AL) is a promising candidate for the treatment of cholangiocarcinoma (bile duct cancer). The study investigated (i) the propensity of capsule formulation of the standardized extract of AL (formulated AL) to modulate mRNA and protein expression and activit...

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Detalles Bibliográficos
Autores principales: Muhamad, Nadda, Plengsuriyakarn, Tullayakorn, Na-Bangchang, Kesara
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9662714/
https://www.ncbi.nlm.nih.gov/pubmed/36374864
http://dx.doi.org/10.1371/journal.pone.0277614