Vitamin D and rosuvastatin alleviate type-II diabetes-induced cognitive dysfunction by modulating neuroinflammation and canonical/noncanonical Wnt/β-catenin signaling

BACKGROUND: Type-II diabetes mellitus (T2DM) is a major risk factor for cognitive impairment. Protecting the brain environment against inflammation, and neurodegeneration, as well as preservation of the BBB veracity through modulating the crosstalk between insulin/AKT/GSK-3β and Wnt/β-catenin signal...

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Detalles Bibliográficos
Autores principales: Muneeb, Muhammad, Mansou, Suzan M., Saleh, Samira, Mohammed, Reham A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2022
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9662739/
https://www.ncbi.nlm.nih.gov/pubmed/36374861
http://dx.doi.org/10.1371/journal.pone.0277457

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9662739/
https://www.ncbi.nlm.nih.gov/pubmed/36374861
http://dx.doi.org/10.1371/journal.pone.0277457

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