Characterization of sequence determinants of enhancer function using natural genetic variation

Sequence variation in enhancers that control cell-type-specific gene transcription contributes significantly to phenotypic variation within human populations. However, it remains difficult to predict precisely the effect of any given sequence variant on enhancer function due to the complexity of DNA...

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Detalles Bibliográficos
Autores principales: Yang, Marty G, Ling, Emi, Cowley, Christopher J, Greenberg, Michael E, Vierbuchen, Thomas
Formato: Online Artículo Texto
Lenguaje:English
Publicado: eLife Sciences Publications, Ltd 2022
Materias:
Chromosomes and Gene Expression
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9662815/
https://www.ncbi.nlm.nih.gov/pubmed/36043696
http://dx.doi.org/10.7554/eLife.76500

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9662815/
https://www.ncbi.nlm.nih.gov/pubmed/36043696
http://dx.doi.org/10.7554/eLife.76500

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