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Regulated degradation of the inner nuclear membrane protein SUN2 maintains nuclear envelope architecture and function

Nuclear architecture and functions depend on dynamic interactions between nuclear components (such as chromatin) and inner nuclear membrane (INM) proteins. Mutations in INM proteins interfering with these interactions result in disease. However, mechanisms controlling the levels and turnover of INM...

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Detalles Bibliográficos
Autores principales: Krshnan, Logesvaran, Siu, Wingyan Skyla, Van de Weijer, Michael, Hayward, Daniel, Guerrero, Elena Navarro, Gruneberg, Ulrike, Carvalho, Pedro
Formato: Online Artículo Texto
Lenguaje:English
Publicado: eLife Sciences Publications, Ltd 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9662817/
https://www.ncbi.nlm.nih.gov/pubmed/36318477
http://dx.doi.org/10.7554/eLife.81573