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High-throughput imaging and quantitative analysis uncovers the nature of plasmid positioning by ParABS

The faithful segregation and inheritance of bacterial chromosomes and low-copy number plasmids requires dedicated partitioning systems. The most common of these, ParABS, consists of ParA, a DNA-binding ATPase and ParB, a protein that binds to centromeric-like parS sequences on the DNA cargo. The res...

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Detalles Bibliográficos
Autores principales: Köhler, Robin, Kaganovitch, Eugen, Murray, Seán M
Formato: Online Artículo Texto
Lenguaje:English
Publicado: eLife Sciences Publications, Ltd 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9662831/
https://www.ncbi.nlm.nih.gov/pubmed/36374535
http://dx.doi.org/10.7554/eLife.78743