N(6)-methyladenosine–Mediated Upregulation of WTAPP1 Promotes WTAP Translation and Wnt Signaling to Facilitate Pancreatic Cancer Progression

Pseudogenes may play important roles in cancer. Here, we explore the mechanism and function of a pseudogene WTAPP1 in the progress of pancreatic ductal adenocarcinoma (PDAC). WTAPP1 RNA was significantly elevated in PDAC and was associated with poor prognosis in patients. Overexpression of WTAPP1 RN...

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Detalles Bibliográficos
Autores principales: Deng, Junge, Zhang, Jialiang, Ye, Ying, Liu, Kaijing, Zeng, Lingxing, Huang, Jingyi, Pan, Ling, Li, Mei, Bai, Ruihong, Zhuang, Lisha, Huang, Xudong, Wu, Guandi, Wei, Lusheng, Zheng, Yanfen, Su, Jiachun, Zhang, Shaoping, Chen, Rufu, Lin, Dongxin, Zheng, Jian
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Association for Cancer Research 2021
Materias:
Tumor Biology and Immunology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9662857/
https://www.ncbi.nlm.nih.gov/pubmed/34362795
http://dx.doi.org/10.1158/0008-5472.CAN-21-0494

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9662857/
https://www.ncbi.nlm.nih.gov/pubmed/34362795
http://dx.doi.org/10.1158/0008-5472.CAN-21-0494

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