Kinobead Profiling Reveals Reprogramming of BCR Signaling in Response to Therapy within Primary CLL Cells

PURPOSE: B-cell receptor (BCR) signaling is critical for the pathogenesis of chronic lymphocytic leukemia (CLL), promoting both malignant cell survival and disease progression. Although vital, understanding of the wider signaling network associated with malignant BCR stimulation is poor. This is rel...

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Detalles Bibliográficos
Autores principales: Linley, Adam J., Karydis, Laura I., Mondru, Anil K., D'Avola, Annalisa, Al Shmrany, Humood, Cicconi, Silvia, Griffin, Rebecca, Forconi, Francesco, Pettitt, Andrew R., Kalakonda, Nagesh, Rawstron, Andrew C., Hillmen, Peter, Steele, Andrew J., MacEwan, David J., Packham, Graham, Prior, Ian A., Slupsky, Joseph R.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Association for Cancer Research 2021
Materias:
Translational Cancer Mechanisms and Therapy
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9662893/
https://www.ncbi.nlm.nih.gov/pubmed/34380642
http://dx.doi.org/10.1158/1078-0432.CCR-21-0161

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9662893/
https://www.ncbi.nlm.nih.gov/pubmed/34380642
http://dx.doi.org/10.1158/1078-0432.CCR-21-0161

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