Phenotypic Composition of Commercial Anti-CD19 CAR T Cells Affects In Vivo Expansion and Disease Response in Patients with Large B-cell Lymphoma

PURPOSE: In clinical trials, the expansion and persistence of chimeric antigen receptor (CAR) T cells correlate with therapeutic efficacy. However, properties of CAR T cells that enable their in vivo proliferation have still to be consistently defined and the role of CAR T bag content has never been...

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Detalles Bibliográficos
Autores principales: Monfrini, Chiara, Stella, Federico, Aragona, Vanessa, Magni, Martina, Ljevar, Silva, Vella, Cristina, Fardella, Eugenio, Chiappella, Annalisa, Nanetti, Francesca, Pennisi, Martina, Dodero, Anna, Guidetti, Anna, Corradini, Paolo, Carniti, Cristiana
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Association for Cancer Research 2022
Materias:
Translational Cancer Mechanisms and Therapy
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9662896/
https://www.ncbi.nlm.nih.gov/pubmed/35583610
http://dx.doi.org/10.1158/1078-0432.CCR-22-0164

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9662896/
https://www.ncbi.nlm.nih.gov/pubmed/35583610
http://dx.doi.org/10.1158/1078-0432.CCR-22-0164

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