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Genetic Determinants of Somatic Selection of Mutational Processes in 3,566 Human Cancers
The somatic landscape of the cancer genome results from different mutational processes represented by distinct “mutational signatures.” Although several mutagenic mechanisms are known to cause specific mutational signatures in cell lines, the variation of somatic mutational activities in patients, w...
Autores principales: | , , , , , , , , , , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
American Association for Cancer Research
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9662923/ https://www.ncbi.nlm.nih.gov/pubmed/34215622 http://dx.doi.org/10.1158/0008-5472.CAN-21-0086 |