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Genetic Determinants of Somatic Selection of Mutational Processes in 3,566 Human Cancers

The somatic landscape of the cancer genome results from different mutational processes represented by distinct “mutational signatures.” Although several mutagenic mechanisms are known to cause specific mutational signatures in cell lines, the variation of somatic mutational activities in patients, w...

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Detalles Bibliográficos
Autores principales: Guo, Jintao, Zhou, Ying, Xu, Chaoqun, Chen, Qinwei, Sztupinszki, Zsófia, Börcsök, Judit, Xu, Canqiang, Ye, Feng, Tang, Weiwei, Kang, Jiapeng, Yang, Lu, Zhong, Jiaxin, Zhong, Taoling, Hu, Tianhui, Yu, Rongshan, Szallasi, Zoltan, Deng, Xianming, Li, Qiyuan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Association for Cancer Research 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9662923/
https://www.ncbi.nlm.nih.gov/pubmed/34215622
http://dx.doi.org/10.1158/0008-5472.CAN-21-0086