Dietary Lactobacillus-Derived Exopolysaccharide Enhances Immune-Checkpoint Blockade Therapy

Microbes and their byproducts have been reported to regulate host health and immune functions. Here we demonstrated that microbial exopolysaccharide produced by Lactobacillus delbrueckii subsp. bulgaricus OLL1073R-1 (EPS-R1) induced CCR6(+) CD8(+) T cells of mice and humans. In mice, ingestion of EP...

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Detalles Bibliográficos
Autores principales: Kawanabe-Matsuda, Hirotaka, Takeda, Kazuyoshi, Nakamura, Marie, Makino, Seiya, Karasaki, Takahiro, Kakimi, Kazuhiro, Nishimukai, Megumi, Ohno, Tatsukuni, Omi, Jumpei, Kano, Kuniyuki, Uwamizu, Akiharu, Yagita, Hideo, Boneca, Ivo Gomperts, Eberl, Gérard, Aoki, Junken, Smyth, Mark J., Okumura, Ko
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Association for Cancer Research 2022
Materias:
Research Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9662940/
https://www.ncbi.nlm.nih.gov/pubmed/35180303
http://dx.doi.org/10.1158/2159-8290.CD-21-0929

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9662940/
https://www.ncbi.nlm.nih.gov/pubmed/35180303
http://dx.doi.org/10.1158/2159-8290.CD-21-0929

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