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STINGing the immune system: lessons learned through a model of G34-mutant pediatric high-grade glioma

Pediatric high-grade gliomas (pHGGs) are aggressive diseases with poor outcomes. The diverse molecular heterogeneity in these rare tumors and inadequate tumor models have limited the development of effective therapies. In this issue of the JCI, Haase et al. produced a genetically engineered mouse mo...

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Detalles Bibliográficos
Autores principales: Hall, Connor P., Cronk, James C., Rubens, Jeffrey A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Clinical Investigation 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9663148/
https://www.ncbi.nlm.nih.gov/pubmed/36377657
http://dx.doi.org/10.1172/JCI164420