Human Dectin-1 deficiency impairs macrophage-mediated defense against phaeohyphomycosis

Subcutaneous phaeohyphomycosis typically affects immunocompetent individuals following traumatic inoculation. Severe or disseminated infection can occur in CARD9 deficiency or after transplantation, but the mechanisms protecting against phaeohyphomycosis remain unclear. We evaluated a patient with p...

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Detalles Bibliográficos
Autores principales: Drummond, Rebecca A., Desai, Jigar V., Hsu, Amy P., Oikonomou, Vasileios, Vinh, Donald C., Acklin, Joshua A., Abers, Michael S., Walkiewicz, Magdalena A., Anzick, Sarah L., Swamydas, Muthulekha, Vautier, Simon, Natarajan, Mukil, Oler, Andrew J., Yamanaka, Daisuke, Mayer-Barber, Katrin D., Iwakura, Yoichiro, Bianchi, David, Driscoll, Brian, Hauck, Ken, Kline, Ahnika, Viall, Nicholas S.P., Zerbe, Christa S., Ferré, Elise M.N., Schmitt, Monica M., DiMaggio, Tom, Pittaluga, Stefania, Butman, John A., Zelazny, Adrian M., Shea, Yvonne R., Arias, Cesar A., Ashbaugh, Cameron, Mahmood, Maryam, Temesgen, Zelalem, Theofiles, Alexander G., Nigo, Masayuki, Moudgal, Varsha, Bloch, Karen C., Kelly, Sean G., Whitworth, M. Suzanne, Rao, Ganesh, Whitener, Cindy J., Mafi, Neema, Gea-Banacloche, Juan, Kenyon, Lawrence C., Miller, William R., Boggian, Katia, Gilbert, Andrea, Sincock, Matthew, Freeman, Alexandra F., Bennett, John E., Hasbun, Rodrigo, Mikelis, Constantinos M., Kwon-Chung, Kyung J., Belkaid, Yasmine, Brown, Gordon D., Lim, Jean K., Kuhns, Douglas B., Holland, Steven M., Lionakis, Michail S.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Clinical Investigation 2022
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9663159/
https://www.ncbi.nlm.nih.gov/pubmed/36377664
http://dx.doi.org/10.1172/JCI159348

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9663159/
https://www.ncbi.nlm.nih.gov/pubmed/36377664
http://dx.doi.org/10.1172/JCI159348

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