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Neonatal hyperoxia in mice triggers long-term cognitive deficits via impairments in cerebrovascular function and neurogenesis

Preterm birth is the leading cause of death in children under 5 years of age. Premature infants who receive life-saving oxygen therapy often develop bronchopulmonary dysplasia (BPD), a chronic lung disease. Infants with BPD are at a high risk of abnormal neurodevelopment, including motor and cogniti...

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Detalles Bibliográficos
Autores principales: Lithopoulos, Marissa A., Toussay, Xavier, Zhong, Shumei, Xu, Liqun, Mustafa, Shamimunisa B., Ouellette, Julie, Freitas-Andrade, Moises, Comin, Cesar H., Bassam, Hayam A., Baker, Adam N., Sun, Yiren, Wakem, Michael, Moreira, Alvaro G., Blanco, Cynthia L., Vadivel, Arul, Tsilfidis, Catherine, Seidner, Steven R., Slack, Ruth S., Lagace, Diane C., Wang, Jing, Lacoste, Baptiste, Thébaud, Bernard
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Clinical Investigation 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9663164/
https://www.ncbi.nlm.nih.gov/pubmed/36136598
http://dx.doi.org/10.1172/JCI146095