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Annexin A2/TLR2/MYD88 pathway induces arginase 1 expression in tumor-associated neutrophils
Myeloid lineage cells suppress T cell viability through arginine depletion via arginase 1 (ARG1). Despite numerous studies exploring the mechanisms by which ARG1 perturbs lymphocyte function, the cellular populations responsible for its generation and release remain poorly understood. Here, we showe...
Autores principales: | , , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
American Society for Clinical Investigation
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9663166/ https://www.ncbi.nlm.nih.gov/pubmed/36377658 http://dx.doi.org/10.1172/JCI153643 |