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Annexin A2/TLR2/MYD88 pathway induces arginase 1 expression in tumor-associated neutrophils

Myeloid lineage cells suppress T cell viability through arginine depletion via arginase 1 (ARG1). Despite numerous studies exploring the mechanisms by which ARG1 perturbs lymphocyte function, the cellular populations responsible for its generation and release remain poorly understood. Here, we showe...

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Detalles Bibliográficos
Autores principales:	Zhang, Huajia, Zhu, Xiaodong, Friesen, Travis J., Kwak, Jeff W., Pisarenko, Tatyana, Mekvanich, Surapat, Velasco, Mark A., Randolph, Timothy W., Kargl, Julia, Houghton, A. McGarry
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	American Society for Clinical Investigation 2022
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9663166/ https://www.ncbi.nlm.nih.gov/pubmed/36377658 http://dx.doi.org/10.1172/JCI153643

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