Cargando…

Cryopreservation does not change the performance and characteristics of allogenic mesenchymal stem cells highly over-expressing a cytoplasmic therapeutic transgene for cancer treatment

BACKGROUND: Mesenchymal stem cells (MSCs) driven gene directed enzyme prodrug therapy is a promising approach to deliver therapeutic agents to target heterogenous solid tumours. To democratize such a therapy, cryopreservation along with cold chain transportation is an essential part of the logistica...

Descripción completa

Detalles Bibliográficos
Autores principales: Ho, Yoon Khei, Loke, Kin Man, Woo, Jun Yung, Lee, Yee Lin, Too, Heng-Phon
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9663191/
https://www.ncbi.nlm.nih.gov/pubmed/36376945
http://dx.doi.org/10.1186/s13287-022-03198-z