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Cryopreservation does not change the performance and characteristics of allogenic mesenchymal stem cells highly over-expressing a cytoplasmic therapeutic transgene for cancer treatment

BACKGROUND: Mesenchymal stem cells (MSCs) driven gene directed enzyme prodrug therapy is a promising approach to deliver therapeutic agents to target heterogenous solid tumours. To democratize such a therapy, cryopreservation along with cold chain transportation is an essential part of the logistica...

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Detalles Bibliográficos
Autores principales:	Ho, Yoon Khei, Loke, Kin Man, Woo, Jun Yung, Lee, Yee Lin, Too, Heng-Phon
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2022
Materias:	Research
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9663191/ https://www.ncbi.nlm.nih.gov/pubmed/36376945 http://dx.doi.org/10.1186/s13287-022-03198-z

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