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Beyond PI3Ks: targeting phosphoinositide kinases in disease

Lipid phosphoinositides are master regulators of almost all aspects of a cell’s life and death and are generated by the tightly regulated activity of phosphoinositide kinases. Although extensive efforts have focused on drugging class I phosphoinositide 3-kinases (PI3Ks), recent years have revealed o...

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Detalles Bibliográficos
Autores principales: Burke, John E., Triscott, Joanna, Emerling, Brooke M., Hammond, Gerald R. V.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9663198/
https://www.ncbi.nlm.nih.gov/pubmed/36376561
http://dx.doi.org/10.1038/s41573-022-00582-5